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Previously Funded Research

2023 LCRF Minority Career Development Award (CDA) in Lung Cancer

Luis Prieto, PhD

Mayo Clinic

Research Project:

Impact of senescent cells on lung tumorigenesis

Summary:

As we age, malignancies, specifically lung cancer, become more prevalent. Yet, the fundamental characteristics of aging that drive cancer development and response to therapy remain largely unknown. Dr. Prieto’s research goal focuses on building a holistic system biology approach to determine what factors that arise with advancing age support tumorigenesis and how we may target them to prevent, postpone, and suppress tumor growth. As an LCRF grantee, Dr. Prieto is working on integrating preclinical models of cancer and aging to investigate how naturally occurring senescent cells promote lung tumor formation.