2005 UALC
Sanford Barsky, MD
University of Nevada School of Medicine
Research Project:
The Bone Marrow Stem Cell Origin of Lung BAC / PAC
Summary:
Dr. Barsky is investigating how stem cells may contribute to the development of bronchioalveolar adenocarcinoma. Previous reports documented patients who received bone marrow transplants to treat leukemia later developed lung cancer �� but the cancer arose from the donated bone marrow. Dr. Barsky will be using two different mouse transplant models to determine if and how transplanted cells from a donor can give rise to lung cancer in the host.
More Content:
Final Report
Dr. Barsky is continuing his work to determine if BAC arises from bone marrow-derived stem cells. The initial method proposed to label the transplanted cells proved ineffective, Dr. Barsky is generating additional mouse models that will utilize a more effective system.