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Previously Funded Research

2009 Free to Breathe Young Investigator Research Grant

Mark Onaitis, MD

Duke University Medical Center

Research Project:

Understanding Tumor-initiating Cells

Summary:

Dr. Onaitis is seeking to better understand the complexity of lung cancer tumors by characterizing tumor-initiating cells and how they respond to certain molecular signals. He will investigate how the type and location of a tumor-initiating cell contributes to the aggressiveness of the cancer. A better understanding of the different types of cells within a tumor and how those cells are affected by cell signals could help develop more effective targeted therapies.